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All scientific sessions will take place at the Vancouver Convention Centre – East Wing:
999 Canada Place
Vancouver, BC V6C 3C1
Tel.: +1-604-689-8232
Fax: +1-604-647-7232
Web: vancouverconventioncentre.com
All sessions will be conducted in English.
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| 12:45-15:00 |
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Date: Thursday, June 24, 2010
Session: SSY - SPECIAL SYMPOSIUM
Location: Vancouver Convention Centre, Exhibit Hall A |
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SSY - SPECIAL SYMPOSIUM: NARROWING THE GAP IN THE TREATMENT AND STUDY OF SLE WORLDWIDE |
| 12:45 |
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Introduction
Matthew H. Liang, USA |
| 12:50-13:00 |
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SSY1 - NARROWING THE GAP IN THE TREATMENT AND STUDY OF SLE WORLDWIDE
Gillian Barclay, Trinidad |
| 13:00-14:00 |
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SSY2 - CURRENT PRACTICES IN THE MANAGEMENT AND MONITORING OF MODERATELY ACTIVE AND LIFE THREATENING SLE
Session Chairs: Cindy H. Flower, Barbados and F Jorge Sanchez-Guerrero, Mexico |
| 13:00 |
SSY2.1 - |
The Caribbean Nations
Cindy H. Flower, Barbados
Desiree Tulloch-Reid, Jamaica
Anselm Hennis, Barbados |
| 13:15 |
SSY2.2 - |
South Africa
Mohamed Tikly, South Africa
Asgar A. Kalla, South Africa
Girish Mody, South Africa |
| 13:30 |
SSY2.3 - |
Latin and South America
F Jorge Sanchez-Guerrero, Mexico
Rafael Raul Vallee, Colombia
Bernardo Pons-Estel, Argentina
Graciela S. Alarcon, USA and Peru |
| 13:45 |
SSY2.4 - |
Southeast Asia
Sujata Sawhney, India
Sandra V Navarra, Philippines |
| 14:00-14:30 |
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SSY3 - OUTREACH
Session Chair: Gillian Barclay, Trinidad |
| 14:00 |
SSY3.1 - |
Cardozo Clinic
Barbara Mittleman, USA
Michael M. Ward, USA |
| 14:12 |
SSY3.2 - |
First Nations
Allen Lehman, Canada
Antonio Avina-Zubieta, Canada
Christine Peschken, Canada |
| 14:24 |
SSY3.3 - |
Vietnam-Seoul Collaboration
Sang-Cheol Bae, South Korea
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| 14:30-15:00 |
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SSY4 - DEVELOPING EVIDENCE-BASED PRACTICE AND SETTING UP CLINICAL RESEARCH INFRASTRUCTURE
Invited Session Chair: Ola Nived, Sweden |
| 14:30 |
SSY4.1 - |
The Latin American Group for the Study of SLE (GLADEL) - a mature research network
Bernardo Pons-Estel, Argentina |
| 14:42 |
SSY4.2 - |
Open resources for research
Open Clinica, USA |
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| 15:15-17:15 |
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Date: Thursday, June 24, 2010
Session: PL - Plenary Session 1
Location: Vancouver Convention Centre, Exhibit Hall A |
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PL1 - CUTTING EDGE OF LUPUS RESEARCH PLENARY SESSION
Invited Session Chairs: Peter Lipsky, USA and Joyce Rauch, Canada |
| 15:15 |
PL1.1 - |
Retroelements as trigger of lupus
Matthias Wabl, USA |
| 15:30 |
PL1.2 - |
Long-lived plasma cells adoptively transferred from NZB/W mice cause immunecomplex nephritis in
immunodeficient Rag1-/- mice
Qingyu Cheng, Germany |
| 15:45 |
PL1.3 - |
Defective migration of tissue-resident dendritic cells: a novel pathogenesis of cutaneous Lupus
Ram Raj Singh, USA |
| 16:00 |
PL1.4 - |
Endothelial progenitor cell dysfunction in SLE
Sahena Haque, UK |
| 16:15 |
PL1.5 - |
Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus
Timothy Niewold, USA |
| 16:30 |
PL1.6 - |
A genetic model for IRF5, autoantibodies, and interferon alpha in systemic lupus erythematosus
Timothy Niewold, USA |
| 16:45 |
PL1.7 - |
Proinflammatory SLE neutrophils induce vascular damage and synthesize IFNs
Mariana Kaplan, USA |
| 17:00 |
PL1.8 - |
Chromatin-activated neutrophils represent a major source of interferon -α
Patrice Decker, Germany |
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| 17:30-19:30 |
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Date: Thursday, June 24, 2010
Session: IC - Industry Course 1
Location: Vancouver Convention Centre, Ballrooms ABC |
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IC1 - HGS INDUSTRY COURSE |
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| 19:30-21:30 |
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LUPUS 2010 WELCOME RECEPTION
Location: Pan Pacific Hotel: Atrium |
| 06:00-06:45 |
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Date: Friday, June 25, 2010
WALK TOGETHER FOR LUPUS |
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| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 1
Location: Vancouver Convention Centre, Meeting Room 8 |
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MTP1 - PERSONALIZED MEDICINE (THERANOSTICS) IN SLE: MYTH OR REALITY?
Marvin J. Fritzler, Canada |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 2
Location: Vancouver Convention Centre, Meeting Room 10 |
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MTP2 - TRADITIONAL AND NEW THERAPIES FOR LUPUS NEPHRITIS
Ricard Cervera, Spain |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 3
Location: Vancouver Convention Centre, Meeting Room 12 |
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MTP3 - CAN WE SCREEN LUPUS PATIENTS FOR THE PRESENCE OF NEUROPSYCHIATRIC INVOLVEMENT USING A SIMPLE QUESTIONNAIRE?
Stefano Bombardieri, Italy |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 4
Location: Vancouver Convention Centre, Meeting Room 15 |
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MTP4 - THE HEART IN SLE AND ANTIPHOSPHOLIPID SYNDROME
Mary-Carmen Amigo, Mexico |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 5
Location: Vancouver Convention Centre, Meeting Room 17 |
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MTP5 - DISCLOSING THE RELEVANCE OF ANTI-RIBOSOMAL P ANTIBODIES IN LUPUS
Eloisa Bonfa, Brazil |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 6
Location: Vancouver Convention Centre, Meeting Room 18 |
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MTP6 - UPDATE ON THE HOPKINS LUPUS COHORT
Michelle A. Petri, USA |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 7
Location: Vancouver Convention Centre, Meeting Room 19 |
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MTP7 - NEUROPSYCHIATRIC LUPUS IN PEDIATRICS – IS IT ALL IN THEIR HEADS?
Marisa Klein-Gitelman, USA, Deborah Levy, Canada |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 8
Location: Pan Pacific Hotel, Meeting Room TBC |
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MTP8
- HOW TO RECOGNIZE AND TREAT SKIN MANIFESTATIONS OF LUPUS
Jan P. Dutz, Canada |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 9
Location: Pan Pacific Hotel, Meeting Room TBC |
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MTP9 - NEW PATHOGENIC ASPECTS AND NEW TREATMENT OPTIONS FOR SLE
Joachim R. Kalden, Germany |
| 07:00-08:00 |
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Date: Friday, June 25, 2010
Session: MTP - Meet the Professor 10
Location: Pan Pacific Hotel, Meeting Room TBC |
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MTP10 - TARGETING CYTOKINES IN SLE
Josef S. Smolen, Austria |
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| 08:00-09:30 |
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Date: Friday, June 25, 2010
Session: PL - Plenary Session 2
Location: Vancouver Convention Centre, Exhibit Hall A |
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PL2 - LUPUS 2010 - THE STATE OF THE ART
Session Chairs: John Esdaile, Canada, Peter Lipsky, USA and Janis McCaffrey, Canada |
| 08:00 |
PL2.1 - |
What have we learned from clinical trials?
Dimitri Boumpas, Greece |
| 08:30 |
PL2.2 - |
Lessons from genetics
Lindsey A. Criswell, USA |
| 09:00 |
PL2.3 - |
Lupus 2010 – Where are we?
Bevra H. Hahn, USA |
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| 09:30-10:00 |
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Coffee Break at Exhibit Hall B |
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| 10:00-11:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 1
Location: Vancouver Convention Centre, Exhibit Hall A |
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CS1 - CARDIOVASCULAR DISEASE IN LUPUS
Invited Session Chairs: Bevra H. Hahn, USA and Susan Manzi, USA |
| 10:00 |
CS1.1 - |
Type I Interferons and premature cardiovascular disease in SLE
Mariana Kaplan, USA |
| 10:25 |
CS1.2 - |
Monocytes from SLE patients with carotid artery plaque and dysfunctional HDL contain upregulated PDGFRbeta that enhances monocyte chemotaxis
Brian Skaggs, USA |
| 10:40 |
CS1.3 - |
Effect of rosuvastatin on homocysteine, hsCRP and endothelial markers in systemic lupus erythematosus (SLE):
a randomized controlled trial
Chi Chiu Mok, Hong Kong |
| 10:55 |
CS1.4 - |
Antibodies towards high density lipoproteins inhibit the anti-inflammatory properties of the lipoproteins
José Delgado Alves, Portugal |
| 11:10 |
CS1.5 - |
High oxidative stress is associated with a 15.8 fold Increased odds for the progression of subclinical atherosclerosis
Maureen McMahon, USA |
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| 10:00-11:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 2
Location: Vancouver Convention Centre, Meeting Room 8 |
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CS2 - T CELLS AND LUPUS
Invited Session Chairs: Joseph E. Craft, USA and Michael Ehrenstein, UK |
| 10:00 |
CS2.1 - |
TH17 in Lupus Nephritis
George C. Tsokos, USA |
| 10:25 |
CS2.2 - |
Frequency and functional activity of Th17, Tc17 and other T cell subsets in systemic lupus erythematosus
Luis Ines, Portugal |
| 10:40 |
CS2.3 - |
Normally occurring NKG2D+ CD4 T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus
Veronika Groh, USA |
| 10:55 |
CS2.4 - |
Increased frequency of circulating CXCR5+CD57+CD4+ follicular T helper cells in patients with systemic lupus erythematosus
Justin Lyman, USA |
| 11:10 |
CS2.5 - |
Lack of PKC kinase activity in T cells induces a lupus-like disease
Gabriela Gorelik, USA |
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| 10:00-11:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 3
Location: Vancouver Convention Centre, Meeting Room 10 |
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CS3 - EPIGENETICS AND LUPUS
Invited Session Chairs: M. Virginia Pascual, USA and Laurence Morel, USA |
| 10:00 |
CS3.1 - |
MicroRNA -mediated immune dysregulation in human lupus
Nan Shen, China |
| 10:25 |
CS3.2 - |
Lupus, DNA methylation and the environment
Bruce C. Richardson, USA |
| 10:50 |
CS3.3 - |
Whole genome methylation scan reveals both hypomethylated and hypermethylated genes in lupus CD4+ T cells
Amr Sawalha, USA |
| 11:05 |
CS3.4 - |
X chromosome signatures associated with the microRNome of human peripheral blood CD4+ T cells; integrating the epi-MicroRNome into the molecular basis of human lupus
Anura Hewagama, USA |
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| 10:00-11:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 4
Location: Vancouver Convention Centre, Meeting Room 11 |
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CS4 - OUTCOMES IN LUPUS
Session Chairs: Matthew H. Liang, USA and Paul Fortin, Canada |
| 10:00 |
CS4.1 - |
Title TBC
Michael Ward, USA |
| 10:25 |
CS4.2 - |
Malignancy in SLE
Sasha Bernatsky, Canada |
| 10:50 |
CS4.3 - |
Statins reduce disease activity scores (SLAM-R) and cumulative organ damage (SLICC) in SLE patients from a multi-center, multi-ethnic, US multi-institutional cohort
Renan Aguilar-Valenzuela, USA |
| 11:05 |
CS4.4 - |
The Georgia Lupus Registry: a population-based estimate of the incidence of SLE in patients with chronic cutaneous lupus
Cristina Drenkard, USA |
| 11:20 |
CS4.5 - |
An introduction on Chinese registry of systemic lupus erythematosus: preliminary data from CSTAR (Chinese SLE treatment and research group)
Xiaofeng Zeng, China |
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| 10:00-11:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 5
Location: Vancouver Convention Centre, Meeting Room 12 |
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CS5 - B CELLS IN LUPUS
Invited Session Chairs: Anne Davidson, USA and Joan E. Wither, Canada |
| 10:00 |
CS5.1 - |
Differential therapeutic impact on B Cell subsets in SLE
Thomas Doerner, Germany |
| 10:25 |
CS5.2 - |
Autoimmunity and tolerance: tracking self-reactivity to its source
Moncef Zouali, France |
| 10:40 |
CS5.3 - |
The plasma cell compartment in NZB/W mice is not responsive to IVIG-treatment
Bimba Hoyer, Germany |
| 10:55 |
CS5.4 - |
The effects of the anti-CD22 monoclonal antibody epratuzumab on peripheral blood B cells and immune responses "in vivo" and immunoglobulin production in vitro
Anthony Shock, UK |
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| 11:30-13:30 |
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Poster Session & Lunch Break
Exhibit Hall B |
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11:30-13:30 |
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Date: Friday, June 25, 2010
Session: PO - Poster Session 1
Location: Vancouver Convention Centre, Exhibit Hall B
Presenters Stand-by Time: 12:30-13:30 |
| 12:00-12:30 |
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POSTER TOURS
Invited Poster Tours Leads:
POSTER TOUR 1
Ricard Cervera, Spain
POSTER TOUR 2
Phillip L. Cohen, USA
POSTER
TOUR 3
Lindsey A. Criswell, USA
POSTER TOUR 4
Anne Davidson, USA
POSTER TOUR 5
Gary Gilkeson, USA
POSTER TOUR 6
Bevra H. Hahn, USA
POSTER TOUR 7
Joachim R. Kalden, Germany
POSTER TOUR 8
Chak-sing Lau, UK
POSTER TOUR 9
Josef S. Smolen, Austria |
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| 12:30-13:00 |
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POSTER DISCUSSIONS
Invited Poster Discussants:
BIOMARKERS
Mary K. Crow, USA
NEPHRITIS
Dimitri Boumpas, Greece
CNS LUPUS: CENTRAL NERVOUS SYSTEM
John Hanly, Canada
GENETICS
John B. Harley, USA
EPIDEMIOLOGY
Rosalind Ramsey Goldman, USA |
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PO1
– POSTER SESSION 1 (
Click Titles to see posters) |
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PO1.A |
APOPTOSIS |
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PO1.B |
BIOMARKERS |
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PO1.C |
CLINICAL
ASPECTS - CNS, RENAL, SKIN, ALL OTHERS |
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PO1.D |
COMPLEMENT |
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PO1.E |
CUTTING
EDGE OF LUPUS RESEARCH |
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PO1.F |
EPIDEMIOLOGY |
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PO1.G |
GENETICS
AND EPIGENETICS |
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PO1.H |
HEALTH
SERVICES |
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PO1.I |
IMMUNOLOGY
- B CELLS |
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PO1.J |
IMMUNOLOGY
- INNATE |
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PO1.K |
IMMUNOLOGY
- T CELLS |
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PO1.L |
IMMUNOLOGY
- TREGS |
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PO1.M |
PATHOGENESIS |
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PO1.N |
SJOGRENS |
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| 12:30-13:30 |
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Date: Friday, June 25, 2010
Session: PTL - Potlatch 1
Location: Vancouver Convention Centre, Meeting Room 15 |
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PTL1 - BEST PRACTICES IN MANAGEMENT OF SLE IN CONSTRAINED ENVIRONMENTS
Session Chair: Cindy H. Flower, Barbados
Co-Chair and Raconteur: Mohamed Tikly, South Africa
Facilitator: Matthew H. Liang, USA |
| 12:30-13:30 |
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Date: Friday, June 25, 2010
Session: PTL - Potlatch 2
Location: Vancouver Convention Centre, Meeting Room 17 |
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PTL2 - FINDING AND DEVELOPING PARTNERSHIPS AND VIRTUAL FOR CLINICAL RESEARCH
Session Chair: Deh-Ming Chang, Taiwan
Co-Chair and Raconteur: Anselm Hennis, Barbados |
| 12:30-13:30 |
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Date: Friday, June 25, 2010
Session: PTL - Potlatch 3
Location: Vancouver Convention Centre, Meeting Room 19 |
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PTL3 - DEVELOPING VIRTUAL MENTORS AND PARTNERS TO IMPROVE PATIENT CARE AND OUTCOMES IN SLE
Session Chair: Sang Cheol Bae, South Korea
Co-Chair and Raconteur: Christine Peschken, Canada |
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| 13:30-15:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 6
Location: Vancouver Convention Centre, Exhibit Hall A |
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CS6 - NEW DRUGS IN DEVELOPMENT
Invited Session Chairs: David Wofsy, USA and John Esdaile, Canada |
| 13:30 |
CS6.1 - |
Belimumab, a BLyS-specific inhibitor, reduced disease activity, flares, and steroid use in patients with seropositive systemic lupus erythematosus (SLE): BLISS-52 study
Sandra Navarra, Philippines |
| 13:45 |
CS6.2 - |
Belimumab, a BLyS-specific inhibitor, reduced disease activity and severe flares in patients with seropositive SLE:
BLISS-76 Study
Richard Furie, USA |
| 14:00 |
CS6.3 - |
Epratuzumab demonstrates clinically meaningful improvements in patients with moderate to severe systemic lupus erythematosus (SLE): Results from EMBLEM™, a phase IIb study
Daniel Wallace, USA |
| 14:15 |
CS6.4 - |
BILAG-measured improvement in moderately and severely affected body systems in patients with systemic lupus erythematosus (SLE) by epratuzumab: Results from EMBLEM™,a phase IIb study
Caroline Gordon, UK |
| 14:30 |
CS6.5 - |
Safety and pharmadynamic response with administration of single and repeat doses of rontalizumab in a phase I, placebo controlled, double blind, dose escalation study in SLE
Jacqueline McBride, USA |
| 14:45 |
CS6.6 - |
Efficacy and safety of Rituximab (RTX) in patients (Pts) with proliferative lupus nephritis (LN): results from randomized, double-blind phase III LUNAR study at week 52
Richard Furie, USA |
| 15:00 |
CS6.7 - |
Repletion of vitamin D deficiency is safe and well-tolerated among African Americans (AAs) with SLE
Diane Kamen, USA |
| 15:15 |
CS6.8 - |
Tacrolimus (Tac) versus mycophenolate mofetil (MMF) for the treatment of membranous lupus nephritis: a randomized controlled trial
Chi Chiu Mok, Hong Kong |
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| 13:30-15:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 7
Location: Vancouver Convention Centre, Meeting Room 8 |
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CS7 - PATHOGENIC MECHANISMS IN LUPUS
Invited Session Chairs: Josef Smolen, Austria and Gary Gilkeson, USA |
| 13:30 |
CS7.1 - |
Follicular Helper T Cells in Immunity and Autoimmunity
Joseph E. Craft, USA |
| 13:55 |
CS7.2 - |
Neutrophil Gelatinase Associated Lipocalin (NGAL) and its role in the pathogenesis of lupus nephritis
Chaim Putterman, USA |
| 14:20 |
CS7.3 - |
Gender Specific Association of X-linked TLR7 with Male SLE
Betty Diamond, USA |
| 14:45 |
CS7.4 - |
The evil trio in lupus pathogenesis
Chandra Mohan, USA |
| 15:10 |
CS7.5 - |
Pristane-induced lupus (PIL) in BALB/c mice: linking severe organ involvement with T-cell response
Georg Stummvoll, Austria |
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| 13:30-15:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 8
Location: Vancouver Convention Centre, Meeting Room 10 |
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CS8 - APOPTOSIS AND LUPUS
Invited Session Chairs: Joachim R. Kalden, Germany and Westley Reeves, USA |
| 13:30 |
CS8.1 - |
Title TBC
David S. Pisetsky, USA |
| 13:55 |
CS8.2 - |
After Apoptosis: Inflammation and Adaptive Immunity
Keith B. Elkon, USA |
| 14:20 |
CS8.3 - |
Clearance deficiency is involved in etiology and pathogenesis of lupus
Martin Herrmann, Germany |
| 14:45 |
CS8.4 - |
The TAM Kinases in lupus and inflammation
Philip L. Cohen, USA |
| 15:10 |
CS8.5 - |
DNase1 activity and circulating nucleosomes in healthy relatives of systemic lupus erythematosus patients
Josep Ordi-Ros, Spain |
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| 13:30-15:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 9
Location: Vancouver Convention Centre, Meeting Room 11 |
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CS9 - GENETICS OF LUPUS
Invited Session Chairs: Edward K. Wakeland, USA and Lindsey
A. Criswell, USA |
| 13:30 |
CS9.1 - |
Genes that make lupus possible
John B. Harley, USA |
| 13:55 |
CS9.2 - |
Title TBC
Betty P. Tsao, USA |
| 14:20 |
CS9.3 - |
Genetics of lupus: what did we learned from the mouse?
Laurence Morel, USA |
| 14:45 |
CS9.4 - |
Exploring the molecular genetics of the (TNFSF4) OX40L association in SLE
Tim Vyse, UK |
| 15:05 |
CS9.5 - |
Genome-wide association study of cardiac manifestations of neonatal lupus identifies risk variants in the ERG, TCF19, C6orf10 and MICB-TNF-AIF1 region
Robert Clancy, USA |
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| 13:30-15:30 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 10
Location: Vancouver Convention Centre, Meeting Room 12 |
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CS10 - T REGS IN LUPUS
Invited Session Chairs: Brian Kotzin, USA and George C. Tsokos, USA |
| 13:30 |
CS10.1 - |
Characterization of regulatory T cells (Treg) and Treg subsets in patients with systemic lupus erythematodes (SLE)
Clemens Scheinecker, Austria |
| 13:45 |
CS10.2 - |
Targeting effector and regulatory T cells in patients with SLE
Michael Ehrenstein, UK |
| 14:10 |
CS10.3 - |
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus
Jens Humrich, Germany |
| 14:25 |
CS10.4 - |
Spontaneous dicer deficiency and altered miRNA in lupus-prone MRL/lpr mice correlates with loss of Treg function
Ram Raj Singh, USA |
| 14:40 |
CS10.5 - |
Increased proportions of CD4+CD25-Foxp3+ T cells in patients with Systemic lupus erythematosus (SLE) correlate with the development of glomerulonephritis
Clemens Scheinecker, Austria |
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| 13:30-15:00 |
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Date: Friday, June 25, 2010
Session: CS - Concurrent Session 11
Location: Vancouver Convention Centre, Meeting Room 18 |
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CS11 - SPECIAL NEEDS AND CHALLENGES FOR CHILDREN AND ADOLESCENTS WITH SLE: A GLOBAL PERSPECTIVE
Session Chair: Ross Petty, Canada |
| 13:30 |
CS11.1 - |
Keynote Speaker
Ross Petty, Canada |
| 13:55 |
CS11.2 - |
APPLE- A CARRA supported study
Laura Schanberg, USA |
| 14:20 |
CS11.3 - |
The UK pediatric lupus group
Michael Beresford, UK |
| 15:45 |
CS11.4 - |
TBA |
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| 15:30-16:00 |
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Coffee Break at Exhibit Hall B |
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| 16:00-17:00 |
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Date: Friday, June 25, 2010
Session: KS - Keynote Speaker 1
Location: Vancouver Convention Centre, Exhibit Hall A |
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KS1 - LESSONS LEARNED FROM ANIMAL MODELS
Session Chair: Peter Lipsky, USA
Keynote Speaker: Edward K. Wakeland, USA |
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| 17:00-19:00 |
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Date: Friday, June 25, 2010
Session: IC - Industry Course 2
Location: Vancouver Convention Centre, Ballrooms ABC |
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IC2 - BMS INDUSTRY COURSE |
| 07:00-08:00 |
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Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 11
Location: Vancouver Convention Centre, Meeting Room 8 |
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MTP11
- OVERVIEW OF CLINICAL TRIALS IN SLE
Daniel J. Wallace, USA |
| 07:00-08:00 |
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Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 12
Location: Vancouver Convention Centre, Meeting Room 10 |
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MTP12 - DIFFERENCES: SLE AS AN EXAMPLE OF A GENDER DIMORPHIC ILLNESS
Robert G. Lahita, USA |
| 07:00-08:00 |
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Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 14
Location: Vancouver Convention Centre, Meeting Room 15 |
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MTP14 - INFECTION/VACCINATION AND SLE
Yehuda Shoenfeld, Israel |
| 07:00-08:00 |
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Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 15
Location: Vancouver Convention Centre, Meeting Room 17 |
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MTP15 - CLINICAL-LABORATORY CORRELATIONS: CONCORDANT OR DISCORDANT?
Murray B. Urowitz, Canada |
| 07:00-08:00 |
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Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 16
Location: Vancouver Convention Centre, Meeting Room 18 |
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MTP16 - PEARLS AND MYTHS IN ANTIPHOSPHOLIPID SYNDROME
Munther A. Khamashta, UK |
| 07:00-08:00 |
|
Date: Saturday, June 26, 2010
Session: MTP - Meet the Professor 17
Location: Vancouver Convention Centre, Meeting Room 19 |
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MTP17 - PEDIATRIC LUPUS NEPHRITIS- NEW ASPECTS IN DIAGNOSIS AND TREATMENT
Hermine Brunner, USA |
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| 08:00-09:30 |
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Date: Saturday, June 26, 2010
Session: PL3 - Plenary Session 3
Location: Vancouver Convention Centre, Exhibit Hall A |
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PL3 - LUPUS EPIDEMIOLOGY AND PATHOGENESIS
Session Chairs: Paul Fortin, Canada and Joan Merrill, USA |
| 08:00 |
PL3.1 - |
Gene expression
M Virginia Pascual, USA |
| 08:30 |
PL3.2 - |
Epidemiology of lupus environment gene interactions
Julia Fridman Simard, Sweden |
| 09:00 |
PL3.3 - |
Interferon and cytokines
Lars Rönnblom, Sweden |
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| 09:30-10:00 |
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Coffee Break at Exhibit Hall B |
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| 10:00-11:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 12
Location: Vancouver Convention Centre, Exhibit Hall A |
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CS12 - LATE BREAKING ABSTRACTS
Invited Session Chairs: Joan Merrill, USA and Murray B. Urowitz, Canada |
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| 10:00-11:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 13
Location: Vancouver Convention Centre, Meeting Room 8 |
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CS13 - LUPUS AND THE ENVIRONMENT
Invited Session Chairs: Bruce C. Richardson, USA and Christine Peschken, Canada |
| 10:00 |
CS13.1 - |
Environmental risk factors for lupus in post-menopausal women: results from the women’s health initiative
Christine G. Parks, USA |
| 10:25 |
CS13.2 - |
Epstein-Barr Virus and Early Events in Lupus Autoimmunity
Judith A. James, USA |
| 10:50 |
CS13.3 - |
The Africa to US lupus gradient 2010: gene vs. Environment
Gary S. Gilkeson, USA |
| 11:15 |
CS13.4 - |
Seasonal variation in the incidence of disease flares in systemic lupus erythematosus (SLE): relationship with weather parameters and ultraviolet light intensity
Chi Chiu Mok, Hong Kong |
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| 10:00-11:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 14
Location: Vancouver Convention Centre, Meeting Room 11 |
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CS14 - CLINICAL EXPERIENCES
Invited Session Chairs: Daniel J. Wallace, USA and Ann Clarke, Canada |
| 10:00 |
CS14.1 - |
An analysis of the metabolic syndrome (MetS) phenotype in UK patients with SLE
Benjamin Parker, UK |
| 10:15 |
CS14.2 - |
Plasma exchange as rescue therapy for critical systemic lupus erythematosus: one center experience
Chun Chi Lu, Taiwan |
| 10:30 |
CS14.3 - |
Efficacy and safety of long-term use of thalidomide for refractory cutaneous lupus
Josefina Cortés-Hernández, Spain |
| 10:45 |
CS14.4 - |
Perceived stress in female patients with systemic lupus erythematosus (SLE)
Stacey Morrison, Canada |
| 11:00 |
CS14.5 - |
Antimalarials have a protective effect against the development of renal disease in Latin American SLE patients
Guillermo Pons-Estel, Argentina |
| 11:15 |
CS14.6 - |
Prolonged serologically active clinically quiescent (SACQ) systemic lupus erythematosus (SLE): clinical and serologic features
Amanda Steiman, Canada |
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| 10:00-11:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 15
Location: Vancouver Convention Centre, Meeting Room 12 |
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CS15 - PREGNANCY AND LUPUS
Invited Session Chair: Carl Laskin, Canada |
| 10:00 |
CS15.1 - |
Mediators and mechanisms of pregnancy complications in patients with Anti-Phospholipid antibodies and patients with lupus: THE PROMISSE STUDY
Jane E. Salmon, USA |
| 10:30 |
CS15.2 - |
Neonatal Lupus: Updates on Pathogenesis, Risk and Reward
Jill P. Buyon, USA |
| 11:00 |
CS15.3 - |
Placental C4d as an indicator of antiphospholipid antibody mediated fetal loss
Danielle Cohen, Netherlands |
| 11:15 |
CS15.4 - |
Markers of cardiovascular function in women with systemic lupus erythematosus (SLE) in pregnancy
Debora Chirico, UK |
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| 10:00-11:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 16
Location: Vancouver Convention Centre, Meeting Room 18 |
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CS16 - OUTCOMES THAT MATTER FOR CHILDREN AND YOUTH WITH SLE: BONE HEALTH, DEVELOPMENT AND QUALITY OF LIFE
Session Chair: Ann Eberhard |
| 10:00 |
CS16.1 - |
Keynote
Ann Eberhard |
| 10:25 |
CS16.2 - |
Bone health
Emily von Scheven |
| 10:50 |
CS16.3 - |
Puberty and sexual development
Kathleen O’Neil |
| 11:05 |
CS16.4 - |
Health Related Quality of life in Pediatric Lupus
Nandini Moorthy, USA |
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| 11:30-13:30 |
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Poster Session and Lunch Break at Exhibit Hall B |
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11:30-13:30 |
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Date: Saturday, June 26, 2010
Session: PO - Poster Session 2
Location: Vancouver Convention Centre, Exhibit Hall B
Presenter Stand-by Time: 12:30-13:30 |
| 12:00-12:30 |
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POSTER TOURS
Invited Poster Tours Leads:
POSTER TOUR 10
Marvin J. Fritzler, Canada
POSTER TOUR 11
Graham R V Hughes, UK
POSTER TOUR 12
David A. Isenberg, UK
POSTER TOUR 13
Elena Massarotti, USA
POSTER TOUR 14
David Pisetsky, USA
POSTER TOUR 15
Jane E. Salmon, USA
POSTER TOUR 16
F Jorge Sanchez-Guerrero, Mexico
POSTER TOUR 17
Laura Schanberg, USA
POSTER TOUR 18
Yehuda Shoenfeld, Israel |
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| 12:30-13:00 |
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POSTER DISCUSSIONS
Invited Poster Discussants:
PAEDIATRICS
TBC
MANAGEMENT OF LUPUS
Ellen Ginzler, USA
NON-BIOLOGICS TREATMENTS
Dafna Gladman, Canada
BIOLOGICS FOR LUPUS
Ronald van Vollenhoven, Sweden |
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PO2
– POSTER SESSION 2 (Click Titles to see posters) |
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PO2.A |
AUTOANTIBODIES |
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PO2.B |
CAUSATION
– ENVIRONMENTAL |
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PO2.C |
CLINICAL
MEASUREMENT |
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PO2.D |
CLINICAL
OUTCOMES |
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PO2.E |
CLINICAL
TRIALS |
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PO2.F |
IMMUNOLOGY
- DENDRITIC CELLS |
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PO2.G |
INTERFERON |
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PO2.H |
MANAGEMENT
- BIOLOGIC THERAPIES |
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PO2.I |
MANAGEMENT
- NON-PHARMACOLOGIC |
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PO2.J |
MANAGEMENT
- TRADITIONAL THERAPIES |
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PO2.K |
MANAGEMENT
- TREATMENT IN DEVELOPMENT |
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PO2.L |
MICROPARTICLES |
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PO2.M |
OVERLAP
SYNDROMES |
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PO2.N |
PAEDIATRIC
LUPUS |
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PO2.O |
PREGNANCY
AND FETAL LOSS |
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| 12:30-13:30 |
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Date: Saturday, June 26, 2010
Session: PTL - Potlatch 4
Location: Vancouver Convention Centre, Meeting Room 15 |
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PTL4 - DESIGNING STUDIES WITH WHAT YOU HAVE
Session Chair: Ole Nived, Sweden
Co-Chair and Raconteur: Graciela Alarcon, USA |
| 12:30-13:30 |
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Date: Saturday, June 26, 2010
Session: PTL - Potlatch 5
Location: Vancouver Convention Centre, Meeting Room 17 |
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PTL5 - FINDING AND DEVELOPING PARTNERSHIPS AND MENTORS FOR CLINICAL RESEARCH
Session Chair: TBA
Co-Chair and Raconteur: TBA |
| 12:30-13:30 |
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Date: Saturday, June 26, 2010
Session: PTL - Potlatch 6
Location: Vancouver Convention Centre, Meeting Room 19 |
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PTL6 - DEVELOPING VIRTUAL MENTORS AND PARTNERS TO IMPROVE PATIENT CARE AND OUTCOMES IN SLE
Session Chair: Sujata Sawhney, India
Co-Chair and Raconteur: TBA |
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| 13:30-15:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 17
Location: Vancouver Convention Centre, Exhibit Hall A |
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CS17 - THE INTERFERON PATHWAY IN LUPUS
Invited Session Chairs: Lars Rönnblom, Sweden and Judith A. James, USA |
| 13:30 |
CS17.1 - |
Interferon-regulated biomarkers of disease activity in SLE
Emily Gillespie, USA |
| 13:55 |
CS17.2 - |
Molecular pathways associated with lupus flare
Mary K. Crow, USA |
| 14:20 |
CS17.3 - |
Cytokine attribution of gene expression and histone H4 acetylation changes in SLE monocytes
Kathleen Sullivan, USA |
| 14:35 |
CS17.4 - |
What are the pathways by which IFN- decreases vasculogenesis in SLE?
Seth Thacker, USA |
| 14:50 |
CS17.5 - |
A genetic variant of TLR9 may impact interferon alpha levels in lupus
Joe Rawdon, USA |
| 15:05 |
CS17.6 - |
Inhibition of the lymphotoxin-beta receptor pathway has unexpected effects on kidney pathology in the adenoviral-IFN BWF1 accelerated model of SLE
Jeffrey Browning, USA |
| 15:20 |
CS17.7 - |
Increased Interferon-alpha activity is associated with increased autoantibody specificities and poor antigen-specific humoral immunity in systemic lupus erythematosus
Lauren Ritterhouse, USA |
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| 13:30-15:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 18
Location: Vancouver Convention Centre, Meeting Room 8 |
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CS18 - AUTOANTIBODIES AND TISSUE PATHOLOGY
Invited Session Chairs: David Pisetsky, USA and Marvin J. Fritzler, Canada |
| 13:30 |
CS18.1 - |
Innate immune mechanisms in experimental lupus
Westley H. Reeves, USA |
| 13:55 |
CS18.2 - |
Cell death in SLE: insights into pathogenesis
Antony Rosen, USA |
| 14:20 |
CS18.3 - |
Antiphospholipid antibodies and thrombophilia in the antiphospholipid syndrome
Tatsuya Atsumi, Japan |
| 14:45 |
CS18.4 - |
B Cells apotopes of Ro60 in Lupus
Thomas P. Gordon, Australia |
| 15:10 |
CS18.5 - |
Anti-heat shock protein 60 autoantibodies are associated with arterial vascular events in patients with anti-phospholipid antibodies
Mélanie Dieudé, Canada |
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| 13:30-15:30 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 19
Location: Vancouver Convention Centre, Meeting Rooms 11/12 |
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CS19 - CLINICAL TRIALS
Invited Session Chairs: Dimitri Boumpas, Greece and Janet Pope, Canada |
| 13:30 |
CS19.1 - |
Some lessons from RA trials to make lupus trials even better
Ronald Van Vollenhoven, Sweden |
| 13:55 |
CS19.2 - |
Trials and Tribulations: What Comes Next?
David Wofsy, USA |
| 14:20 |
CS19.3 - |
Outcome measures in SLE trials
Caroline P. Gordon, UK |
| 14:45 |
CS19.4 - |
Title TBC
Richard A. Furie, USA |
| 15:10 |
CS19.5 - |
Flare assessment in systemic lupus erythematosus (SLE) patients treated with Rituximab in the phase II/III EXPLORER trial
Joan Merrill, USA |
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| 13:30-15:00 |
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Date: Saturday, June 26, 2010
Session: CS - Concurrent Session 20
Location: Vancouver Convention Centre, Meeting Room 18 |
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CS20 - WORLD WIDE FINDINGS IN PAEDIATRIC LUPUS
Session Chairs: TBA |
| 13:30 |
CS20.1 - |
Defining and measuring global flares in juvenile systemic lupus erythematosus
Rina Mina, USA |
| 13:45 |
CS20.2 - |
Psychiatric illness of systemic lupus erythematosus in childhood
Siok Hoon Lim, Canada |
| 14:00 |
CS20.3 - |
Performance of a new health-related quality of life (HRQOL) measure in pediatric lupus across five countries
L. Nandini Moorthy, USA |
| 14:15 |
CS20.4 - |
Primary immunodeficiencies in juvenile systemic lupus erythematosus patients
Adriana Jesus, Brazil |
| 14:30 |
CS20.5 - |
Bone mineral density in childhood and adult onset systemic lupus erythematosus (SLE):
a cross-sectional comparative study
Chi Chiu Mok, Hong Kong |
| 14:45 |
CS20.6 - |
Variability of mycophenolic acid (MPA) pharmacokinetics (PK) in childhood-onset systemic lupus erythematosus (cSLE) may be partly explained by UGT genotype
A. Carmela Sagcal-Gironella, USA |
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| 15:30-16:00 |
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Coffee Break at Exhibit Hall B |
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| 16:00-17:00 |
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Date: Saturday, June 26, 2010
Session: KS - Keynote Speaker 2
Location: Vancouver Convention Centre, Exhibit Hall A |
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KS2 - PITFALLS IN THE DEVELOPMENT OF NEW LUPUS DRUGS
Session Chair: Peter Lipsky, USA
Keynote Speaker: Brian Kotzin, USA |
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| 18:00-21:00 |
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POTLATCH RECEPTION & AWARDS
Location: Vancouver Convention Centre, Ballroom ABC |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 18
Location: Vancouver Convention Centre, Meeting Room 8 |
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MTP18 - PRACTICAL ASPECTS OF USING MYCOPHENOLATE MOFETIL IN RENAL/NONRENAL SLE
Ellen Ginzler, USA |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 19
Location: Vancouver Convention Centre, Meeting Room 10 |
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MTP19 - OUTCOME MEASURES IN SLE
Dafna D. Gladman, Canada |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 20
Location: Vancouver Convention Centre, Meeting Room 12 |
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MTP20 - FAILURES IN ANTIPHOSPHOLIPID SYNDROME
Graham R V Hughes, UK |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 21
Location: Vancouver Convention Centre, Meeting Room 15 |
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MTP21 - SAFETY OF EXOGENOUS ESTROGENS IN SLE
F Jorge Sanchez-Guerrero, Mexico |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 22
Location: Vancouver Convention Centre, Meeting Room 17 |
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MTP22 - ANTIPHOSPHOLIPID ANTIBODIES- PROBLEMS IN BABIES AND TEENS
Rolando Cimaz, Italy, Barry Myones, USA |
| 07:00-08:00 |
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Date: Sunday, June 27, 2010
Session: MTP - Meet the Professor 23
Location: Vancouver Convention Centre, Meeting Room 18 |
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MTP23 - CHALLENGES AND REWARDS: CARING FOR ADOLESCENT LUPUS PATIENTS
Lori B. Tucker, Canada |
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| 08:00-09:30 |
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Date: Sunday, June 27, 2010
Session: PL - Plenary Session 4
Location: Vancouver Convention Centre, Exhibit Hall A |
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PL4 - SLE - OF MICE AND WOMEN
Invited Session Chairs: John Esdaile, Canada and Laurence Morel, USA |
| 08:00 |
PL4.1 - |
How has murine lupus informed us about human lupus?
Joan E. Wither, Canada |
| 08:30 |
PL4.2 - |
Treatment of nephritis
Daniel Tak Mao Chan, China |
| 09:00 |
PL4.3 - |
New therapeutic targets in SLE
David A. Isenberg, UK |
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| 09:30-10:00 |
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Coffee Break at Exhibit Hall B |
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| 10:00-12:00 |
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Date: Sunday, June 27, 2010
Session: Year in Review
Location: Vancouver Convention Centre, Exhibit Hall A |
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REVIEW OF PROGRESS SINCE SHANGHAI, WORKSHOP REPORTS & AWARDS
Session Chair: Paul Fortin, Canada |
| 10:00 |
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Basic
Anne Davidson, USA |
| 10:45 |
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Clinical
Ian N. Bruce, UK |
| 11:30 |
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Wrap-up
Paul Fortin, Canada |
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| 12:00-14:00 |
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Date: Sunday, June 27, 2010
Session: IC - Industry Course 3
Location: Vancouver Convention Centre, Ballrooms ABC |
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IC3 - UCB INDUSTRY COURSE |
| * Program is subject to change |
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